ITP RevBio Receives FDA approval for a first in-human Clinical Trial!•ITP PI, Dr. Isabelle Lombaert wins the 2023 University of Michigan Medical School’s Frankel Innovation Initiative Award!•RevBio Awarded a $3.4 Million NIH Grant•Congratulations to our ITP teams presenting at Forsyth dentech 2023!•SAVE THE DATE! 2024 MPWRM Resource Center Stakeholder's Summit - April 8-9, 2024•SAVE THE DATE! 2023 DOCTRC Retreat - December 4-6, 2023 in Los Angeles, CA•MPWRM Resource Center and DOCTRC were highlighted in the keynote talk at NIDCR's 75th anniversary event, NIDCR at 75: Celebrating the Past, Charting the Future•RevBio Receives ISO 13485 Certification for its Quality Management System!•GreenMark Biomedical Launches CrystLCare™ Biorestorative, Fluoride-Free!•GreenMark Biomedical's LumiCare Carries Detection Rinse makes the cover of Dental Products Report!

Manufacturing Services

Prototyping and Process for Manufacturing, Wyss Institute

Ability to produce:

  • Biopolymer based hydrogels/cryogels
  • Polymer-based porous scaffolds
  • Polymer-based nano/micro particles
  • Lipid-based nano/micro particles
  • Polymer-based aggregates

Analytical expertise:

  • Drug release profiling by HPLC, SEC, GPC, Ion Exchange chromatography, fluorescence, luminescence, absorbance, Native-PAGE, SDS-PAGE, Western Blots, Agarose Gels, ELISAs/Titers, LC/MS, numerous other product specific assays including cell based assays.
  • Material characterization: Dynamic light scattering, rheology, NMR, IR, SEM, TEM, numerous other product specific assays.

Translational Capabilities:

  • Process and analytical qualification and validation capabilities
  • Support good laboratory practice (GLP) toxicity & biocompatibility testing, regulatory submissions, and in some cases early stage human clinical trials.

Instrumentation:

  • LC/MS, fluorescent/absorbance plate-reader
  • HPLC (reverse phase, size exclusion, ion exchange, hydrophilic)
  • Dynamic Light Scattering DLS
  • Zeta potential (Zetasizer)
  • Rheometer

 Contact Mutsumi Yoshida, Ph.D at yoshidam@umich.edu for specific guidance and/or additional information about the manufacturing services or facilities available.

 

INTERDISCIPLINARY TRANSLATIONAL PROJECTS PROGRAM

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